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Citrus Sinensis CAS 520-27-4 Yellow Diosmin Powder EP8.3 Assay 90

Product Details

Place of Origin: China (Mainland)

Brand Name: YHF

Certification: 520-27-4

Payment & Shipping Terms

Minimum Order Quantity: Minimum standard package, for the detail, please refer to "regular package"

Packaging Details: 25kg/drum

Delivery Time: 30 work days after receiving firm order.

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Specifications
Highlight:

CAS 520-27-4 Diosmin Powder

,

Citrus Sinensis Diosmin Powder

,

EP8.3 Yellow Diosmin Powder

CAS:
520-27-4
Specification:
EP8.3
Herb Source:
Citrus Sinensis
Appearance:
Yellow Powder
MV:
608.54
MF:
C28H32O15
Storage:
Cool And Dry
Packaging:
25Kg/drum
CAS:
520-27-4
Specification:
EP8.3
Herb Source:
Citrus Sinensis
Appearance:
Yellow Powder
MV:
608.54
MF:
C28H32O15
Storage:
Cool And Dry
Packaging:
25Kg/drum
Description
Citrus Sinensis CAS 520-27-4 Yellow Diosmin Powder EP8.3 Assay 90

CAS 520-27-4 Diosmin Yellow Powder EP8.3 Assay 90 Used Medicinal

 

What is the function and usage of Diosmin

 

Diosmin is a commonly used drug in vascular surgery, which can treat the related diseases caused by venous lymphatic insufficiency, such as heaviness, pain, swelling and discomfort in the legs. For hemorrhoids also has a certain effect, the role is to improve venous return, increase the surface tension of blood vessels, promote blood circulation.

Use 2 tablets twice a day, if in the acute phase, 3 times a day, 2 tablets each time. Take it twice a day at noon and in the evening, which helps to absorb the drug and avoid nausea and vomiting. For drug allergy, or try not to use diosmin.

 

Specification:

 

DETERMINATIONS SPECIFICATIONS
Appearance Grayish-yellow or light yellow hygroscopic powder.
Solubility Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in ethanol(96 per cent). It dissolves in dilute solutions of alkali hydroxides.

Identification

(2.2.24 & 2.2.29Ph Eur.1611)

A. Infrared absorption spectrophotometry

Camparison:diosmin CRS

  B. The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution (a)
Iodine(2.2.36&2.5.10Ph Eur.1611) ≤0.1%

Related substances

(HPLC)

(2.2.29Ph Eur.1611)

Impurity A (Acetoisovanillone) ≤0.5%
Impurity B (Hesperidin) ≤ 4.0%
Impurity C ( Isorhoifolin) ≤3.0%
Impurity D (6-Iododiosmin) ≤0.6%
Impurity E (Linarin) ≤3.0%
Impurity F (Diosmetin) ≤2.0%
Any unspecified impurity ≤0.4%
Total of impurities ≤8.5%

Heavy metals

(2.4.8 Method C Ph Eur.1611)

≤20ppm
Hg (AAS) ≤0.10ppm
Water (2.5.12Ph Eur.1611) ≤6.0%
Sulphated ash (2.4.14Ph Eur.1611) ≤0.2%

Assay on anhydrous basis

(2.2.29Ph Eur.1611)

90.0%~102.0% (on anhydrous basis)
Pyridine (2.4.24Ph Eur.1611) ≤200ppm

Particle size

(by laser granulometry)

80%<2 micron

Microbiological test

(CP2010)

Total bacteria count :≤1000cfu/g
Moulds and yeasts :≤100cfu/g
Salmonella: Negative
E.Coli :Negative

Remarks: In a word, we can produce as per the client`s specific rquirements like particle size,color,solubility, signal heavy metal under Eu rules No629/2008, the other contaminants under EC1881/2006 and residual solvent under directive EC32/2009.

 

                                        Manufacturing process

 

Citrus Sinensis CAS 520-27-4 Yellow Diosmin Powder EP8.3 Assay 90 0

Package:

 

1Kg/Foil Bag(Net Weight 1Kg,Gross Weight 1.2Kg);

 

25Kg/Fiber Drum(Net Weight 25Kg,Gross Weight 29.10Kg)

 

 

Our Advantages:

 

1. Free Sample(10-20g Or Enough To Detection) And Unconditional Assume Response

 

2. 100% Natural Prroduct, Without Any Synthetize Ingredient

 

3. Manufacturer Direct Supply, Provide OEM, R&D Service

 

4. ISO/HACCP/KOSHER/GMPs/FDA

 

5. Leading Plant Extract Manufacturer In China

 

Citrus Sinensis CAS 520-27-4 Yellow Diosmin Powder EP8.3 Assay 90 1

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