Product Details
Place of Origin: China (Mainland)
Brand Name: YHF
Certification: 520-27-4
Payment & Shipping Terms
Minimum Order Quantity: Minimum standard package， for the detail, please refer to "regular package"
Packaging Details: 25kg/drum
Delivery Time: 30 work days after receiving firm order.
CAS: |
520-27-4 |
Specification: |
EP8.3 |
Herb Source: |
Citrus Sinensis |
Appearance: |
Yellow Powder |
MV: |
608.54 |
MF: |
C28H32O15 |
Storage: |
Cool And Dry |
Packaging: |
25Kg/drum |
CAS: |
520-27-4 |
Specification: |
EP8.3 |
Herb Source: |
Citrus Sinensis |
Appearance: |
Yellow Powder |
MV: |
608.54 |
MF: |
C28H32O15 |
Storage: |
Cool And Dry |
Packaging: |
25Kg/drum |
CAS 520-27-4 Diosmin Yellow Powder EP8.3 Assay 90 Used Medicinal
What is the function and usage of Diosmin
Diosmin is a commonly used drug in vascular surgery, which can treat the related diseases caused by venous lymphatic insufficiency, such as heaviness, pain, swelling and discomfort in the legs. For hemorrhoids also has a certain effect, the role is to improve venous return, increase the surface tension of blood vessels, promote blood circulation.
Use 2 tablets twice a day, if in the acute phase, 3 times a day, 2 tablets each time. Take it twice a day at noon and in the evening, which helps to absorb the drug and avoid nausea and vomiting. For drug allergy, or try not to use diosmin.
Specification:
| DETERMINATIONS | SPECIFICATIONS |
| Appearance | Grayish-yellow or light yellow hygroscopic powder. |
| Solubility | Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in ethanol(96 per cent). It dissolves in dilute solutions of alkali hydroxides. |
|
Identification (2.2.24 & 2.2.29Ph Eur.1611) |
A. Infrared absorption spectrophotometry Camparison:diosmin CRS |
| B. The principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with reference solution (a) | |
| Iodine(2.2.36&2.5.10Ph Eur.1611) | ≤0.1% |
|
Related substances (HPLC) (2.2.29Ph Eur.1611) |
Impurity A (Acetoisovanillone) ≤0.5% |
| Impurity B (Hesperidin) ≤ 4.0% | |
| Impurity C ( Isorhoifolin) ≤3.0% | |
| Impurity D (6-Iododiosmin) ≤0.6% | |
| Impurity E (Linarin) ≤3.0% | |
| Impurity F (Diosmetin) ≤2.0% | |
| Any unspecified impurity ≤0.4% | |
| Total of impurities ≤8.5% | |
|
Heavy metals (2.4.8 Method C Ph Eur.1611) |
≤20ppm |
| Hg (AAS) | ≤0.10ppm |
| Water (2.5.12Ph Eur.1611) | ≤6.0% |
| Sulphated ash (2.4.14Ph Eur.1611) | ≤0.2% |
|
Assay on anhydrous basis (2.2.29Ph Eur.1611) |
90.0%~102.0% (on anhydrous basis) |
| Pyridine (2.4.24Ph Eur.1611) | ≤200ppm |
|
Particle size (by laser granulometry) |
80%<2 micron |
|
Microbiological test (CP2010) |
Total bacteria count :≤1000cfu/g |
| Moulds and yeasts :≤100cfu/g | |
| Salmonella: Negative | |
| E.Coli :Negative |
Remarks: In a word, we can produce as per the client`s specific rquirements like particle size,color,solubility, signal heavy metal under Eu rules No629/2008, the other contaminants under EC1881/2006 and residual solvent under directive EC32/2009.
Manufacturing process
Package:
1Kg/Foil Bag(Net Weight 1Kg,Gross Weight 1.2Kg);
25Kg/Fiber Drum(Net Weight 25Kg,Gross Weight 29.10Kg)
Our Advantages:
1. Free Sample(10-20g Or Enough To Detection) And Unconditional Assume Response
2. 100% Natural Prroduct, Without Any Synthetize Ingredient
3. Manufacturer Direct Supply, Provide OEM, R&D Service
4. ISO/HACCP/KOSHER/GMPs/FDA
5. Leading Plant Extract Manufacturer In China
