Sichuan Yuanhongfu Technology Co., Limited

It is human nature to love beauty, delaying aging can be said to be the appeal of all women, and among the aging of various organs, the aging of the skin is the most obvious. Therefore, slowing down the aging of the skin is the dream of the majority of women. Scientists have discovered that a natural compound called quercetin can slow down the aging of skin cells. Let's take a look.   Quercetin is a natural flavonoid that can be extracted from the flowers, leaves and fruits of many plants. Current studies have found that quercetin has multiple biological activities, among which the most interesting is its antioxidant effect.   So how does quercetin exert its antioxidant effect? It is a natural chelating agent that can chelate iron in the body and reduce iron overload in the body, thereby reducing oxidative damage caused by iron overload. According to the research, after supplementing iron-containing food and taking quercetin orally, the protein expression returned to normal, and the oxidative damage of the mice was significantly reduced. The strong comprehensive antioxidant capacity of quercetin may be related to the structural characteristics of polyhydroxy and hydroxy unformed glycosides. The antioxidant mechanism of quercetin is mainly to scavenge free radicals and superoxide anions, and there are three main ways: (1) complex with superoxide anions to reduce the generation of oxygen free radicals; (2) complex with iron ions to prevent (3) Inhibit aldose reductase and reduce the consumption of reduced coenzyme II (NADPH), thereby improving the body's antioxidant capacity. To put it simply, it reduces the formation of oxygen free radicals, allowing our skin to avoid aging caused by oxidation, thereby improving skin quality.   Quercetin is a flavonoid compound, which is a kind of Chinese medicinal material with a wide range of uses, also known as quercetin and quercetin. It has a good expectorant, antitussive effect, and has a certain antiasthmatic effect. In addition, it has the functions of lowering blood pressure, enhancing capillary resistance, reducing capillary fragility, lowering blood lipids, expanding coronary arteries, and increasing coronary blood flow. For the treatment of chronic bronchitis. It also has adjuvant therapy for patients with coronary heart disease and hypertension.  

Hesperidin is a citrus bioflavonoid that contains flavonoid glycosides, which are composed of flavonoids and rutin. Lemons and peppers contain high amounts of hesperidin and are mainly concentrated in the peel and film. Sweet oranges are one of the richest food sources, and their pulp is richer in flavonoids. The role of hesperidin Hesperidin and flavonoid glycosides are mainly used in Europe to treat venous insufficiency and hemorrhoids. Hesperidin and rutin help reduce capillary permeability and are anti-inflammatory. They are both classified as vitamin P. Animal tests have found that hesperidin may be beneficial in the treatment of vascular disease, cancer and some autoimmune diseases, and can be used as an anti-allergy drug in people. It is an important nutrient that works with vitamin C to keep collagen healthy and avoid sagging skin and wrinkles caused by collagen breakdown. Hesperidin is most effective only when it works synergistically with vitamin C, otherwise its efficacy is minimal. Hesperidin is a vitamin drug that can supplement vitamins and other trace elements. After using it, the body will feel very relaxed, and the psychological pressure and the impact of physical diseases will be alleviated. The taste of hesperidin is not particularly bitter, so it will not cause nausea and vomiting and other adverse phenomena, or use after meals can promote intestinal digestion and absorption. If you encounter malnutrition and your body's immune system is too low, you can adapt to it, but if it is the first time to use it, you should follow the doctor's advice.

Hesperetin is a natural flavonoid, widely present in the fruit of Rutaceae. The main active ingredient in the fruit of the plant, hesperetin is the glycosyl ligand of hesperidin. It contains ketone carbonyl group, ether group, methoxy group and multiple phenolic hydroxyl groups, which makes it have a wide range of pharmacological effects. Hesperetin does not accumulate in any organ, and is safe to use with no obvious side effects. Early studies on the pharmacological effects of hesperetin mainly focused on antibacterial, anti-inflammatory, anti-oxidative, anti-viral, anti-allergic, lipid-regulating, immune-enhancing and anti-cancer aspects. In recent years, it has been reported that hesperetin and its derivatives also have anti-Alzheimer's disease, anti-Parkinson's disease, anti-hyperglycemia, anti-venom hemagglutinin, anti-lung, kidney, liver fibrosis and some new tumor inhibition, etc.   Pharmacological effects:   1）Anti-tumor effect: Hesperetin has anti-oxidative effect, which can prevent cancer caused by genetic changes caused by these factors. Promote the efflux of P-glycoprotein-mediated drugs from tumor cells, and flavonoids (hesperetin, etc.) can change the permeability of the blood-brain barrier to vincristine, and it is also related to its concentration. Low concentrations of flavonoids can reduce the uptake of vincristine by brain capillary endothelial cells; on the contrary, high concentrations can promote it.     2）Hypolipidemic effect: Hesperetin can inhibit the function of cholesterol generation enzymes and esterase enzymes, thereby achieving the effect of lowering blood lipids.     3) Antioxidant effect: Hesperetin can avoid the harm caused by peroxidation by removing peroxynitrite ions.   4) Anti-inflammatory effect: Hesperetin can inhibit the mediating effect of inflammatory mediators, thereby indirectly inhibiting the inflammatory response. Compared with hesperidin, hesperetin has a stronger anti-inflammatory effect, and hesperetin C7 linked to rutose has an effect on its anti-inflammatory activity.   5) Cardiovascular protection: Hesperetin has the effect of reducing blood lipids and vascular permeability, and can prevent thrombosis. Hesperetin can also protect endothelial cells from hypoxia by stimulating certain mitochondrial enzymes such as succinate dehydrogenase, preventing coagulation caused by endothelial cell necrosis and inducing thrombosis. In addition, hesperetin promotes antiplatelet coagulation activity by inhibiting the phosphorylation of PLCγ2 and its downstream signaling, which can prevent the formation of thrombus and is beneficial to the cardiovascular system.

Sweeteners are food additives that impart sweetness to soft drinks. Sweeteners can be divided into nutritive sweeteners and non-nutritive sweeteners according to their nutritional value; according to their sweetness, they can be divided into low-sweetness sweeteners and high-sweetness sweeteners; Divided into natural sweeteners and synthetic sweeteners.   The main functions of sweeteners in food are as follows: 1）Taste: Sweetness is one of the indicators of many foods. In order to make food and beverages taste palatable, a certain amount of sweetener needs to be added. 2）For the adjustment and enhancement of flavor, sweetness is generally required in cakes; in beverages, there is a "sugar-acid ratio" for flavor adjustment. Sweeteners allow products to achieve good flavor while retaining fresh flavor. 3)The formation of flavor, sweetness and the flavor of many foods are complementary to each other, and the flavor of many products is produced by the combination of flavor substances and sweeteners, so many foods are added with sweeteners.   There are many types of sweeteners, which can be divided into: according to their sources, they can be divided into natural sweeteners and artificial sweeteners; according to their nutritional value, they can be divided into nutritive sweeteners and non-nutritive sweeteners; according to their chemical Structure and properties are divided into sugar and non-saccharide sweeteners.   Although sugars such as glucose, fructose, sucrose, maltose, starch sugar and lactose are also natural sweeteners, they are often regarded as food raw materials because they have been eaten by humans for a long time and are important nutrients, and are not used as food additives in China.   Non-sugar sweeteners include natural sweeteners and artificial sweeteners. Natural sweeteners include stevia, licorice, disodium glycyrrhizinate, tripotassium glycyrrhizinate and trisodium glycyrrhizinate. Synthetic sweeteners include saccharin, sodium saccharin, sodium cyclamate, aspartame, alitame, and the like.   Naringin dihydrochalcone (NADC) is a new type of sweetener. Compared with sucrose, it has the characteristics of high sweetness, low calorific value, non-toxicity and safety. It can be used in food, medicine and daily chemical industry. But without the debittering properties of NHDC.   The taste is refreshing, the aftertaste is long-lasting, and it has a special fragrance, which has a good effect of shielding bitterness, especially suitable for dairy products, fats and oils, and frozen foods.   In processed vegetables, jellies, jams, non-alcoholic beverages, chewing gum, toothpaste and buccal tablets. As a substitute for sugar, it can also reduce the intake of sugar in the human body, and is suitable for obese patients and diabetics.